4,116 research outputs found

    SOLID WASTE DISPOSAL IN RURAL AREAS: ECONOMIC IMPLICATIONS

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    Community/Rural/Urban Development,

    Urak Lawoi' : bbasic structures and a dictionary

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    Mode of access: Internet

    Stochastic Regular Grazing Bifurcations

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    A grazing bifurcation corresponds to the collision of a periodic orbit with a switching manifold in a piecewise-smooth ODE system and often generates complicated dynamics. The lowest order terms of the induced Poincare map expanded about a regular grazing bifurcation constitute a Nordmark map. In this paper we study a normal form of the Nordmark map in two dimensions with additive Gaussian noise of amplitude, epsilson [e]. We show that this particular noise formulation arises in a general setting and consider a harmonically forced linear oscillator subject to compliant impacts to illustrate the accuracy of the map. Numerically computed invariant densities of the stochastic Nordmark map can take highly irregular forms, or, if there exists an attracting period-n solution when e = 0, be well approximated by the sum of n Gaussian densities centred about each point of the deterministic solution, and scaled by 1/n, for sufficiently small e > 0. We explain the irregular forms and calculate the covariance matrices associated with the Gaussian approximations in terms of the parameters of the map. Close to the grazing bifurcation the size of the invariant density may be proportional to the square-root of e, as a consequence of a square-root singularity in the map. Sequences of transitions between different dynamical regimes that occur as the primary bifurcation parameter is varied have not been described previously.Comment: Submitted to: SIAM J. Appl. Dyn. Sy

    A photoelectron diffraction investigation of vanadyl phthalocyanine on Au(1 1 1)

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    Scanned-energy mode photoelectron diffraction using the O 1s and V 2p emission perpendicular to the surface has been used to investigate the orientation and internal conformation of vanadyl phthalocyanine (VOPc) adsorbed on Au(1 1 1). The results confirm earlier indications from scanning tunnelling microscopy that the Vdouble bond; length as m-dashO vanadyl bond points out of, and not into, the surface. The Vdouble bond; length as m-dashO bondlength is 1.60 ± 0.04 Å, not significantly different from its value in bulk crystalline VOPc. However, the V atom in the adsorbed molecule is almost coplanar with the surrounding N atoms and is thus pulled down into the approximately planar region defined by the N and C atoms by 0.52 (+0.14/−0.10) Å, relative to its location in crystalline VOPc. This change must be attributed to the bonding interaction between the molecule and the underlying metal surface

    Creating the Future of Health

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    Creating the Future of Health is the fascinating story of the first fifty years of the Cumming School of Medicine at the University of Calgary. Founded on the recommendation of the Royal Commission on Health Services in 1964 the Cumming School has, from the very beginning, focused on innovation and excellence in health education. With a pioneering focus on novel, responsive and systems-based approaches, it was one of the first faculties to pilot multi-year training programs in family medicine and remains one of only two three-year medical schools in North America. Drawing on interviews with key players and extensive research into documents and primary material, Creating the Future of Health traces the history of the school through the leadership of its Deans. This is a story of perseverance through fiscal turbulence, sweeping changes to health care and health care education, and changing ideas of what health services are and what they should do. It is a story of triumph, of innovation, and of the tenacious spirit that thrives to this day at the Cumming School of Medicine

    Examining the patient and caregiver experience with diazepam nasal spray for seizure clusters: Results from an exit survey of a phase 3, open-label, repeat-dose safety study

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    BACKGROUND: Ideal rescue treatments for acute treatment of seizure clusters should be easy to administer, so it is important to assess user perceptions of these treatments. Diazepam nasal spray is designed to have a rapid, noninvasive, and socially acceptable route of administration. Patient and caregiver (including care partner) responses to surveys from a phase 3 safety study of diazepam nasal spray are reported. METHODS: The study enrolled patients aged 6-65 years with seizure clusters. Surveys distributed to patients and caregivers at study end, completion, or discontinuation collected data on comfort using diazepam nasal spray outside the home, timing of administration and return to their usual selves, and comfort of use compared with rectal diazepam. Safety was assessed. RESULTS: Of 175 patients enrolled at the October 31, 2019, interim cutoff, 158 received diazepam nasal spray. Sixty-seven (42.4%) patients and 84 (53.2%) caregivers responded to the surveys (including 35 matched pairs). Most patients (78.8%, 52/66) responded that they were very comfortable doing activities outside the home with diazepam nasal spray available; 59.4% of patients returned to their usual selves within an hour of administration. Twenty-seven (40.3%) of these patients reported self-administration, 48% doing so at the first sign of a seizure. Administration of diazepam nasal spray was rated extremely or very easy by 93.8% of caregivers. Safety profile was consistent with diazepam rectal gel; no patient discontinued owing to treatment-emergent adverse events. Nasal discomfort was typically mild and transient. Among patients who had used diazepam rectal gel, most were not at all comfortable using it outside the home (86.7%) or at home (64.5%) compared with diazepam nasal spray, whereas caregivers reported that diazepam rectal gel was not at all easy to use compared with diazepam nasal spray. CONCLUSIONS: This survey from the phase 3 safety study of diazepam nasal spray shows that patients and caregivers were satisfied with, and more comfortable using, diazepam nasal spray than rectal diazepam in public. NCT02721069

    A comparative framework: how broadly applicable is a 'rigorous' critical junctures framework?

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    The paper tests Hogan and Doyle's (2007, 2008) framework for examining critical junctures. This framework sought to incorporate the concept of ideational change in understanding critical junctures. Until its development, frameworks utilized in identifying critical junctures were subjective, seeking only to identify crisis, and subsequent policy changes, arguing that one invariably led to the other, as both occurred around the same time. Hogan and Doyle (2007, 2008) hypothesized ideational change as an intermediating variable in their framework, determining if, and when, a crisis leads to radical policy change. Here we test this framework on cases similar to, but different from, those employed in developing the exemplar. This will enable us determine whether the framework's relegation of ideational change to a condition of crisis holds, or, if ideational change has more importance than is ascribed to it by this framework. This will also enable us determined if the framework itself is robust, and fit for the purposes it was designed to perform — identifying the nature of policy change
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